Cluster of Excellence: Microbiomes drive Planetary Health

(FWF COE 7, 2023-2028)

Our vision is to break down the walls between environmental (green) and medical (red) microbiome research in Austria and to cross-fertilize each other, resulting in enormous benefits across fields through new, unified conceptual advances and technological innovations.

Involved team members
Charlotte Neumann, Alexander Mahnert, Christina Kumpitsch



SFB Immunometabolism

(FWF, 2020- 2024)

Our tasks
Understand role of archaea and their cells components, proteins and metabolites on macrophage activity
Understand the interplay of the human microbiome and macrophages; role of the mirobiome in cachexia

Involved team members
Torben K├╝hnast, Viktoria Weinberger



RESPImmun

(FWF, 2021- 2025)

Our tasks

The goal is to understand the role of the human respiratory system microbiome in the context of lung diseases and immunomodulatory mechanisms. 


Involved team members
Tejus Shinde, Christina Kumpitsch 

The mother-microbiome-child interaction
(funded by FWF TRAMIC, PI: E. Jantscher-Krenn)
 

The influence of hospital regimens on the development of the microbiomes of preterm-born, very-low-birthweight infants

(funded by FWF and other sources)


Our tasks
Understand the transfer of anaerobes to infants' microbiomes after vaginal/ C-section birth
Understand the impact of probiotics, antibiotics and feeding strategies in the early days of preterm gut development


Involved team members
Charlotte Neumann


Publications

Mar 2023
Neumann CJ, Mahnert A, Kumpitsch C, Kiu R, Dalby MJ, Kujawska M, Madl T, Kurath-Koller S, Urlesberger B, Resch B, Hall LJ, Moissl-Eichinger C. Clinical NEC prevention practices drive different microbiome profiles and functional responses in the preterm intestine. Nat Commun. 2023 Mar 11;14(1):1349. doi: 10.1038/s41467-023-36825-1. PMID: 36906612; PMCID: PMC10008552. Link

Closed projects, other projects


  • The archaeome in gastrointestinal disorders - AGAD (funded by FWF, 2019-2023,  P 32697): Understand the  role of archaea in the human gastrointestinal tract. Link


  • Archaea on skin (funded by FWF, 2018-2022, P 30796): Understand and cultivate archaea from skin. Link


  • The Nose-Brain Axis (funded by FWF, 2017-2021): Understand the role of the nasal microbiome for the sense of smell. Link


  • Hospital resistome project: Understand the microbiome dynamics and resistome diversity in various hospital settings (surgery rooms, intensive care units)


  • Planetary Protection and spacecraft/ astronaut microbiomes: Understand the level of contamination of space-craft targeting evolutionary interesting solar system bodies, understand the requirements for maintaining a healthy human microbiome during long-term spaceflight