Preprint (25.07.2024): 

The Influence of Breastfeeding on Infant Gut Microbiome Development 

We conducted a longitudinal examination of the taxonomic and functional dynamics of the oral and gastrointestinal (GIT) microbiomes in 30 healthy infants over their first year of life. Our focus included often-overlooked aspects such as the development of archaeal and anaerobic microbiomes. Check it out: Link

The dynamics of the female microbiome: unveiling abrupt changes of microbial domains across body sites from prepartum to postpartum phases (2024)

Another (little) baby paper out! We show that the maternal microbiome undergoes substantial changes in the transition from before to after birth, which might be long-lasting. A focus on mothers' health and healing process is needed.
We tracked 30 women from their pregnancy to 1 month after birth, profiling their oral, urinary, and vaginal microbiomes, as well as their archaeome, mycobiome, and urinary metabolome.
Interestingly, the oral microbiome stabilizes rapidly after birth, but the urogenital microbiome suffers from a significant loss of Lactobacillus after birth. Findings suggest the need for probiotic (?) interventions to optimize postpartum recovery.
Check it out: Link

Preprint (31.04.2024): 

Expanding the cultivated human archaeome by targeted isolation of novel Methanobrevibacter strains from fecal samples 

In this manuscript, we report on a cultivation pipeline that allowed us to isolate methanogenic archaea from virtually all fecal samples. Together with our great collaborators, we characterized the archaea and genomes obtained and gained a first understanding of their functions. Check it out:
Link

Exploring the human archaeome: its relevance for health and disease, and its complex interplay with the human immune system (2024)

In the FEBS journal we summarize the current knowledge on the human archaeome - immune system interplay:
Link

Interindividual differences in aronia juice tolerability linked to gut microbiome and metabolome changes—secondary analysis of a randomized placebo-controlled parallel intervention trial (2024)

We supported the study of our colleagues  on Aronia juice and its effect on gut microbiome and metabolome - now out in the Microbiome journal:
Link

Preprint (12.02.2024) : 

Age-Related Dynamics of Methanogenic Archaea in the Human Gut Microbiome: Implications for Longevity and Health

Archaea might be involved in healthy aging - we analyzed Austrian and Italian adults, elderlies and centenarians, and found interesting functions for the involved methanoarchaea:
Link

Reduced olfactory performance is associated with changed microbial diversity, oralization, and accumulation of dead biomaterial in the nasal olfactory area (2024)

In ASM Spectrum we report about the correlation of the nasal microbiome and the olfactory performance. Congratulations to first author Christina Kumpitsch and the entire team!
Link
Summary of content

Clinical NEC prevention practices drive different microbiome profiles and functional responses in the preterm intestine (2023)

Our new publication is out in Nature Communications:  "Clinical NEC prevention practices drive different microbiome profiles and functional responses in the preterm intestine". Amazing work by first-author Charlotte Neumann, great collaboration with Neonatology @Medunigraz and the Hall Lab (TU Munich/ Quadram). 
Link to publication 
Summary of content
Press release MedUni Graz
Press release Quadram Institute

Acute appendicitis manifests as two microbiome state types with oral pathogens influencing severity (2023)

Our new publication is out in Gut Microbes: "Acute appendicitis manifests as two microbiome state types with oral pathogens influencing severity". Excellent work by first-author Marcus Blohs, great collaboration with the  Department of Paediatric and Adolescent Surgery @MedUni Graz.
Link to publication
Summary of content